The 50-share NSE Nifty broke below the crucial 7,500 level and settled lower by 45.65 points, or 0.61 percent, at 7,486.15.
Mumbai: In a climb-down from its five-week high, the benchmark Sensex on Thursday took its first hit in seven sessions by falling nearly 171 points even as the Nifty slipped below the 7,500-mark following profit-booking amid mixed global leads.
The rupee was on a higher footing at 67.07 against the dollar, which stemmed the losses.
The 30-share barometer opened higher and rose further before profit-booking kicked in, which pulled it down to 24,623.34 at the close, a loss of 170.62 points, or 0.69 percent.
The index had risen about 1,792 points in the past six sessions, its longest winning run since October last year.
The 50-share NSE Nifty broke below the crucial 7,500 level and settled lower by 45.65 points, or 0.61 percent, at 7,486.15. Intra-day, it shuttled between 7,447.40 and 7,547.10.
"The market capped the winning streak as anxiety over ECB policy meet led to profit booking. ECB is expected to provide a stimulus... Additionally, concerns over Chinese economy and swing in oil prices are adding to volatility," said Vinod Nair, Head-Fundamental Research, Geojit BNP Paribas.
The upmove in the previous six sessions mostly came on the back of continued foreign fund inflows and expectations that RBI would reduce the policy rate.
Of the 30-share Sensex pack, 19 ended with losses and 11 turned higher.
Moreover, a mixed closing at other Asian markets and a lower opening in Europe showed up in sentiment.
Investors waited for a policy update from the European Central Bank.
Shares of BHEL melted the most falling 2.93 percent to Rs 104.50, followed by RIL (2.92 percent) at Rs 1,011.50.
The country's second-largest IT exporter Infosys too slid 2.51 per cent to Rs 1,148.90 after reports that some of its founders sold off shares.
Other that contributed to the fall include GAIL, L&T, SBI, ITC, Axis Bank, Dr Reddy's, M&M and Hero MotoCorp. Asian Paints, HDFC, Maruti Suzuki, Bharti Airtel, Cipla, Sun Pharma, NTPC, ONGC, Bajaj Auto, Tata Steel and Tata Motors rose, thus cushioning the fall.
The BSE capital goods index took the biggest knock, down 1.70 percent, followed by IT 1.33 percent, technology 1.21 percent, oil and gas 1.05 percent and realty 1.04 percent.
In line with the overall trends, the broader markets witnessed selling, with the mid-cap index declining 0.32 percent and small-cap shedding 0.18 percent.
Foreign portfolio investors (FPIs) bought shares worth a net Rs 462.86 crore yesterday, as per provisional data.