Gwyneth Paltrow, Madonna`s friendship over?

Los Angeles: They have been best of buddies since 1999 but it seems that Hollywood star Gwyneth Paltrow`s friendship with Madonna has run its course.

The Oscar-winning actress, who once referred to Madonna "like an older sister", has reportedly stopped talking to the singer after a series of fall outs, Us magazine reported.

"They don`t speak. I can`t tell you exactly why they had the falling out," a source told the magazine.

The reports about their fall out comes soon after Paltrow dropped hints during a recent interview that she had a fight with a friend.

"I can be mean. I can cave in to gossip. I can ice people out and I can definitely harbour revenge. In fact, I`m having a situation right now with a friend where I`m feeling pretty angry. But revenge is corrosive and it doesn`t make me feel good," the `Iron Man 2` star had said in an interview to Vogue magazine.

At the time it was widely believed that she was referring to Madonna.

In fact in the same interview she made a dig at the singer when noted that trainer Tracey Anderson, was no longer working with Madonna.

"It`s good that she doesn`t train Madonna any more. It was too much. She keeps people waiting - it takes up your whole day."

Although Madonna`s rep denies the "breakup," the source says things went bad slowly for the duo after Madonna split from Guy Ritchie in 2008, leaving "Gwyneth and Madonna with less in common."

Paltrow, who is married to UK-born singer Chris Martin since 2003, and Madonna reportedly began to cut their ties after the singer relocated to New York following her divorce with Ritchie.