Frozen human embryos can yield viable stem cells
Washington: Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research.
Kamthorn Pruksananonda and coauthors from Chulalongkorn University and Chulalongkorn Memorial Hospital, Bangkok, Thailand, demonstrated that ES cells derived from frozen embryos have a similar ability to differentiate into multiple cell types—a characteristic known as pluripotency—as do ES cells derived from fresh embryos.
“The importance of this study is that it identifies an alternative source for generating new embryonic stem lines, using embryos that have been in long-term storage,” says Editor-in-Chief Jane Taylor, PhD, MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland.
The study was published online in the BioResearch Open Access website.