Aspirin may slow decline in brain capacity
London: A daily dose of acetylsalicylic acid equivalent to a fourth of an aspirin may slow the decline in intellectual capacity among elderly individuals with high cardiovascular risk, according to a study.
Over a five year period, researchers at Sahlgrenska Academy, University of Gothenburg, Sweden studied how intellectual capacity changes among 681 elderly women (70 to 92 years) with heightened risk of suffering from a heart attack, vascular spasm or stroke.
Of the 681 women, 129 received a low daily dose of acetylsalicylic acid, equivalent to a fourth of an aspirin, to prevent heart disease. The Gothenburg study shows that acetylsalicylic acid also slowed decline in brain capacity among the elderly women.
In the study the women underwent various tests to measure their physical health and intellectual capacity, such as language and memory tests.
"At the end of the five year examination period mental capacity had declined among all the women and the portion that suffered from dementia was equally large in the entire group. However, the decline in brain capacity was significantly less and occurred at a slower pace among the women who received acetylsalicylic acid," said Silke Kern, researcher at Sahlgrenska Academy.
The effect remained even when age, genetic factors and use of anti-inflammatory drugs were taken into account.
In addition to preventing heart disease, acetylsalicylic acid has been shown to be effective against cancer according to several scientific studies. It is common practice in many countries to treat women at risk for heart disease with a small dose of acetylsalicylic acid.
Silke Kern emphasizes that the study is an observational study and that more research is necessary before any definitive conclusions can be made.
The study was published in British Medical Journal Open.