Ancestry cures disease!

Scientists have shown that genetic variation in a small region of chromosome 11 determine rates of PUFA metabolism.

London: A new study involving an Indian-origin researcher has suggested that ancestry plays a vital role in different populations with regards to disease prevention and treatment.

The latest research from Wake Forest Baptist Medical Center and the laboratories of Floyd H. `Ski` Chilton, Ph.D., professor of physiology and pharmacology and director of the Center for Botanical Lipids and Inflammatory Disease Prevention, and Rasika Mathias, Sc.D, assistant professor of medicine and epidemiology at Johns Hopkins University School of Medicine, reveals how humans of different ancestry process a certain type of fat called polyunsaturated (PUFA) fat.

Chilton and other groups of scientists have shown that genetic variation in a small region of chromosome 11, known as the FADS cluster, plays a critical role in determining rates of PUFA metabolism in populations of European and Asian ancestry.

"This is an important example of why it is critical to advance the field of personalized nutrition," Chilton said.

"Understanding which nutrients may be healthy for one population, but not for another will be essential to optimizing public health."

"It is critical to study groups such as African Americans because they bear a large proportion of the public health burden of many of the chronic complex diseases of inflammation," he added.

The study will be published in The British Journal of Nutrition.


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