Air pollution may lead to brain cancer
Washington: A team of researchers is set to conduct a study to determine if several potentially toxic compounds that exist in polluted air are capable of entering the brain from the bloodstream and causing brain cancer.
The research by scientists at the Maxine Dunitz Neurosurgical Institute and Department of Neurosurgery at Cedars-Sinai will be done in laboratory mice and will focus on three - naphthalene, butadiene and isoprene - that often are associated with polluted air.
Cedars-Sinai researchers and others have used high-tech systems to detect genes and proteins involved in the development of brain cancers.
They have studied molecular changes and interactions considered "brain tumour pathways" that lead from defective gene activity to cancer generation in the brain.
The researchers also have identified certain genes that appear to support cancer stem cells. Like normal stem cells, cancer stem cells have the ability to self-renew and generate new cells, but instead of producing healthy cells, they create cancer cells.
The air pollution study is intended to determine whether up to 12 months of ongoing exposure to air pollution causes molecular changes in the brain that are consistent with the development of brain tumor pathways; if toxins associated with air pollution can cross the brain's natural defense mechanism - the blood-brain barrier - and enter the brains of animals; and whether this exposure activates genes and proteins that support brain cancer stem cells.
In the new study, researchers will examine tissue exposed to pollutants at three months, six months and 12 months to determine if there is a change with longer exposure compared to shorter.
More from India
More from World
More from Sports
More from Entertaiment
- Rajasthan: Gujjars revive reservation agitation, block rail track
- J Jayalalithaa sworn-in as Chief Minister of Tamil Nadu
- Dr Subhash Chandra Show: Aspiring for more than what you have!
- ISIS to buy first nuclear weapon from Pak?
- Mumbai: CCTV captures assailant with gun at Film City
- Mathura SSP receives death threat letter, message for PM Modi
- BJP now central pole of Indian politics: Arun Jaitley
- Maharashtra FDA sends Maggi noodles for lab testing
- Watch: Fast N Facts @ 7:30pm
- Reservation issue: Police register case against Bainsla, 20 others
- Haridwar: Hotel Radisson Blu sealed for polluting Ganga
- Delhi: Two killed in road accident in New Ashok Nagar
- Girl in Punjab's Pathankot quit studies for fear of eve-teasing
- Zee Media exclusive chat with 'Welcome to Karachi' cast
- Zee Media exclusive interview with Haryana CM Manohar Lal Khattar
- Goa Board SSC Exam Results 2015 announced
- ISIS close to buying nuclear weapon from Pakistan?
- Manohar Parrikar visits forward areas along LoC, reviews security situation
- Credibility of Prime Minister's Office restored by BJP, says Arun Jaitley
- ISIS justifies raping slave girls, says Michelle Obama is 'worth $40'
- IPL 2015 Final: Mumbai Indians vs Chennai Super Kings - Preview
- 'Unhappy' Celina Jaitley asks Sunny Leone to move out?
- Arvind Kejriwal to highlight AAP govt's 100 days work on Monday
- CBSE Results 2015: 10th board exam results to be declared on May 27
- BJP's plan for one-year celebration: 200 big rallies, 5,000 public meetings
- IPL 8 Final: We need to be at our best against Mumbai, says Michael Hussey
- Heatwave leaves 153 dead in Telangana, Andhra Pradesh
- Heatwave kills 223 in AP, Telangana, Chandrababu Naidu announces compensation; Delhi records hottest day
- IPL 2015 Final: MI vs CSK - As it happened...
- 'Tanu Weds Manu Returns' starts on a good note at the Box Office!