Lack of vitamin D linked to hypertension
Washington: A new study led by an India researcher has confirmed that low levels of vitamin D can trigger hypertension.
Although observational studies have already shown this link, a large-scale genetic study was necessary before the cause and effect could be proven, the annual conference of the European Society of Human Genetics (ESHG) said.
Dr. Vimal Karani S, from the Institute of Child Health, University College London, London, UK, said that data from the D-CarDia collaboration, involving 35 studies, over 155,000 individuals, and numerous centres in Europe and North America, showed that those with high concentrations of 25-hydroxyvitamin D (25(OH)D) had reduced blood pressure and therefore a reduced risk of hypertension.
"We knew from earlier observational studies that low 25(OH)D concentrations were likely to be associated with increases in blood pressure and hypertension, but correlation is not causality", he said.
"Additionally, randomised controlled trials of vitamin D supplementation in humans have produced inconsistent effects on cardiovascular outcomes. The whole picture was somewhat confused, and we decided to try to figure it out once and for all," he added.