Probiotic bugs may help treat depression: Scientists
Washington: Scientists have identified a type of gut bacteria that can directly influences the brain, a finding they say could lead to new ways to control depression and other psychiatric disorders.
Researchers have long suspected that the gut was somehow linked with the brain, since bowel disorders are linked with stress-related psychiatric disorders such as anxiety and depression in people.
To learn more, a team at the University College Cork in Ireland fed laboratory mice with Lactobacillus rhamnosus JB-1, a bug that naturally lives in human gut.
The researchers found that the mice, which were given the bug-laced broth, displayed significantly less behaviour linked with stress, anxiety and depression than mice fed plain broth.
Bacteria-fed mice also had significantly lower levels of the stress hormone corticosterone in response to stressful situations such as mazes, LiveScience reported.
As mice serve as good models for understanding aspects of the human brain, the the findings can be replicated in humans too, the researchers said.
"By affecting gut bacteria, you can have very robust and quite broad-spectrum effects on brain chemistry and behaviour," study researcher John Cryan said.
Cryan said: "Without overstating things, this does open up the concept that we could develop therapies that can treat psychiatric disorders by targeting the gut.
"You could take a yogurt with a probiotic in it instead of an antidepressant," he added.
"Now, that would not be an everyday yogurt -- I`m not saying you should go out to the supermarket and try doing this," he cautioned.
"The effect depends on the strain of probiotic you use. The hope would be, though, that this could have less side effects than drugs."