Protein linked to kidney disease identified
Washington: A protein linked to kidney failure has been identified which could pave the way for new interventions to treat the disease.
The protein plays a crucial role in kidney fibrosis, a condition that leads to kidney failure, researchers from Mount Sinai School of Medicine said.
The research team studied three mouse models of kidney fibrosis.
One group of mice contained HIV viral proteins incorporated into their genome.
The second group was injected with a high dose of folic acid.
In the third group, kidney filtration was blocked in one kidney.
All of these factors caused kidney fibrosis, Xinhua reported.
The researchers compared the genetic material of mice having kidney fibrosis with those that did not suffer from the condition.
They found that HIPK2, a protein kinase, or regulator, was highly active in the mice with kidney fibrosis.
When HIPK2 eliminated, fibrosis was less prominent and the condition of the mice significantly improved.
The study was published this week in Nature Medicine.
More from India
More from World
More from Sports
More from Entertaiment
- Vyapam Scam: IMA president Sudhir Tiwari fears life threat
- Vyapam Scam: Mystery over journalist Akshay Singh's death continues
- Panel discussion on RSS's 'Muslim Rashtriya Manch' first Iftaar party
- Jhansi police launches ‘Citizen Cop’ android app
- MPs spend more than Rs 25 cr taxpayers' money on study tours: DNA reports
- Vyapam scam: MP medical college dean found dead in hotel, body sent for post-mortem
- Vyapam scam: Last rites of journalist Akshay Singh performed; MP CM assures of SIT probe
- Photographer captures International Space Station flying across moon
- PM Narendra Modi holds talks with Uzbek leader
- Chile stun Argentina to win first Copa America crown