Secondhand smoke may up risk for respiratory illness in kids
Washington: Exposure to secondhand smoke decreases sensitivity to cough-eliciting respiratory irritants in otherwise healthy children and adolescents, according to new research from the Monell Center.
The findings may help to explain why children of smokers are more likely to develop pneumonia, bronchitis and other diseases and also are more likely to experiment with smoking during adolescence.
“Cough protects our lungs from potentially damaging environmental threats, such as chemicals and dust. Living with a parent who smokes weakens this reflex, one of the most vital of the human body,” said Julie Mennella, Ph.D., a developmental biologist at Monell who co-directed the study with Monell sensory scientist Paul Wise, Ph.D.
Adult smokers are known to have a less sensitive cough reflex relative to non-smokers, meaning that it takes more irritation to elicit a cough in the smokers.
The Monell research team conducted the current study to ask if the cough reflex of children and adolescents who are regularly exposed to secondhand smoke is affected in a similar fashion.
In the study, 38 healthy children aged 10-17 years old inhaled increasing concentrations of capsaicin from a nebulizer. Capsaicin is the burning ingredient in chili peppers and a potent chemical stimulus for cough. Seventeen of the youth were regularly exposed to smoke in the home, while 21 were never exposed to smoke at home.
Youth regularly exposed to secondhand smoke required twice as much capsaicin to trigger cough as did non-exposed children, meaning that the exposed children were less sensitive to the irritating environmental stimulus. A similar finding was true for the parents, confirming earlier findings.
An insensitive cough reflex could make exposed children less able to cope with environmental threats, which could in turn play a role in their increased risk for developing respiratory illness.
It is also possible that an insensitive cough reflex could increase the risk of adolescents acquiring a smoking habit by making experimentation with smoking less unpleasant.
The study appeared in Tobacco and Nicotine Research.
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