Two-drug combo to help in fight against HIV
Washington: A research team has devised a new delivery system for a combination of two FDA approved drugs, which could help effectively treat HIV.
The discovery, which allows for a combination of decitabine and gemcitabine to be delivered in pill form, marks a major step forward in patient feasibility for the drugs, which previously had been available solely via injection or intravenous therapy (IV).
Steven Patterson, Ph.D., professor at the Center for Drug Design at the University of Minnesota, said that if a person has a condition that requires them to take a medication every day, as many patients with HIV do, they wouldn`t want to have to take that medication via daily injection.
University of Minnesota researchers first announced decitabine and gemcitabine could potentially combine to treat HIV in research published in August 2010.
The drug combination was shown to work by lethal mutagenesis that could obliterate HIV by causing the virus to mutate to a point where it was no longer infectious. For some patients, HIV`s ability to quickly mutate and evolve can result in drug resistance.
For patients who have developed resistance to currently available HIV treatments, the decitabine-gemcitabine drug combination could prove an effective alternative and secondary line of defense.
In addition to a potentially effective treatment for humans with HIV, the combination also shows potential to treat cats with leukemia.
The study has been published online in the journal Antiviral Chemistry and Chemotherapy.
Download the all new Zee News app for Android and iOS to stay up to date with latest headlines and news stories in Politics, Entertainment, Sports, Technology, Business and much more from India and around the world.
More from India
More from World
More from Sports
More from Entertaiment
- Entire Indian force can't defend Kashmir from terrorists: Farooq Abdullah
- Woman cop transferred within 24 hours of spat with Haryana minister Anil Vij
- It's a reality, Muslim youths from South India more attracted to ISIS: Kiren Rijiju
- Sheena Bora murder: Why did Indrani send servant to Kolkata to get illegal drugs?
- PM Narendra Modi meets journalists at Diwali Milan