Washington: Researchers have suggested a novel strategy that could potentially form a primary component of a universal influenza vaccine capable of providing long-lasting protection.Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin (HA) protein.Yearly vaccines are made by growing the flu virus in eggs. The viral envelope proteins, including HA, are cleaved off and used as the vaccine, but vary from year to year, depending on what flu strains are prevalent. However, high mutation rates in envelope HA proteins result in the emergence of new viral types each year, which elude neutralization by pre-existing antibodies in the body (specifically the HA proteins` specific receptor binding sites that are the targets of neutralizing antibodies).On the other hand, other immune cell types are capable of mediating protection through recognition of other, more conserved parts of HAs or highly conserved internal proteins in the influenza virus.
High voter turnout in 5th phase of Lok Sabha polls
FIR against Misa for disturbing poll process
RCB play hard and party hard too: Mallya
Ananth Kumar calls Congress a non-performer across India