London: A new study led by an Indian-origin researcher has identified six new genes that are responsible for the early onset of type-2 diabetes in South Asians (India, Pakistan, Sri Lanka and Bangladesh).The findings give scientists new leads in the search for diagnostic markers and drug targets to prevent and treat this major disease.People of South Asian ancestry are up to four times more likely than Europeans to develop type 2 diabetes, which is a major risk factor for heart disease and stroke. The researchers from around the world examined the DNA of 18,731 people with type 2 diabetes and 39,856 healthy controls. The genomes of the participants were analysed to look for locations where variations were more common in those with diabetes.The results identified six positions where differences of a single letter in the genetic code were associated with type 2 diabetes, suggesting that nearby genes have a role in the disease.
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