Washington:Scientists may have hit upon an effective way to block asthma attacks by identifying the two most significant biological triggers that bring them on.Researchers from the Universities of California-San Francisco (UCSF), Johns Hopkins and Duke universities demonstrate that these two triggers for asthma are tied to a specific calcium-activated chloride channel, called TMEM16A.They regulate airway secretions and smooth muscle contraction, the two major factors linked with asthma attacks, according to the journal "Proceedings of the National Academy of Sciences". "Maybe if we could inhibit both of these processes by blocking this one channel, we could affect the two symptoms of asthma," said senior study author Jason Rock, assistant professor of anatomy at UCSF.
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