Washington: A new study has revealed that copper is one of the main environmental factors that is responsible for the onset and enhancement of Alzheimer`s disease. The study by University of Rochester Medical Center (URMC) Department of Neurosurgery showed that copper can accumulate in the brain and cause the blood brain barrier to break down, resulting in the toxic accumulation of the protein amyloid beta, a by-product of cellular activity.Using both mice and human brain cells researchers conducted a series of experiments that have pinpointed the molecular mechanisms by which copper accelerates the pathology of Alzheimer`s disease.The research team - "dosed" normal mice with copper over a three month period. The exposure consisted of trace amounts of the metal in drinking water and was one-tenth of the water quality standards for copper established by the Environmental Protection Agency.
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