Washington: Taking muscle-building dietary supplement creatine may help improve recovery in women battling stubborn major depression.Creatine is an amino acid made in the human liver, kidneys, and pancreas. It is also found in meat and fish.Researchers from three South Korean universities and the University of Utah have found that women with major depressive disorder (MDD) who augmented their daily antidepressant with 5 grams of creatine responded twice as fast and experienced remission of the illness at twice the rate of women who took the antidepressant alone.The study means that taking creatine under a doctor`s supervision could provide a relatively inexpensive way for women who haven`t responded well to SSRI (selective serotonin reuptake inhibitor) antidepressants to improve their treatment outcomes.“If we can get people to feel better more quickly, they`re more likely to stay with treatment and, ultimately, have better outcomes,” said Perry F. Renshaw, M.D., Ph.D., M.B.A, USTAR professor of psychiatry at the U of U medical school and senior author on the study.If these initial study results are borne out by further, larger trials, the benefits of taking creatine could directly affect many Utahns. The depression incidence in Utah is estimated to be 25 percent higher than the rest of the nation, meaning the state has an even larger proportion of people with the disease.
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