Washington: Researchers have identified the dose of dengue virus in human blood that is required to infect mosquitoes when they bite.Mosquitoes are essential for transmitting the virus between people so the findings have important implications for understanding how to slow the spread of the disease.By defining the threshold of the amount of virus needed for transmission, the research also provides a target that experimental dengue vaccines and drugs must prevent the virus from reaching in order to be successful at preventing the spread of disease during natural infection.Recent estimates indicate that there are 390 million infections of dengue across the globe each year and with no vaccine or specific treatment available, current measures to prevent the spread of disease are focused on controlling the mosquito vector.
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