London: Researchers at UT Southwestern Medical Center have reported discovery of a specific gene that regulates the heart`s ability to regenerate after injuries.Scientists led by Dr. Hesham Sadek have demonstrated that the gene Meis1 regulates the regenerative capability of newborn hearts.The function of the gene, called Meis1, in the heart was not known previously."We found that the activity of the Meis1 gene increases significantly in heart cells soon after birth, right around the time heart muscle cells stop dividing," said Dr. Hesham Sadek, assistant professor of internal medicine in the division of cardiology, and senior author of the study."Based on this observation we asked a simple question: If the Meis1 gene is deleted from the heart, will heart cells continue to divide through adulthood? The answer is `yes`," asserted Dr. Sadek.
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