Washington: A new study has found a genetic link between chronic pancreatitis and alcohol consumption.Researchers from the University of Pittsburgh School of Medicine and more than 25 other health centers across the United States found a genetic variant on chromosome X near the claudin-2 gene (CLDN2) that predicts which men who are heavy drinkers are at high risk of developing chronic pancreatitis."The discovery that chronic pancreatitis has a genetic basis solves a major mystery about why some people develop chronic pancreatitis and others do not," said David C. Whitcomb, M.D., professor of medicine, cell biology and physiology, and human genetics at the University of Pittsburgh School of Medicine and lead author of the report."We also knew there was an unexpected higher risk of men developing pancreatitis with alcohol consumption, but until now we weren`t sure why. Our discovery of this new genetic variant on chromosome X helps explain this mystery as well," he stated.
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