Washington: An international research team coordinated at the IRCM in Montreal has found a possible alternative treatment for lymphoid leukemia. Led by Dr. Tarik Moroy, the IRCM`s President and Scientific Director, the team discovered a molecule that represents the disease`s "Achilles` heel" and could be targeted to develop a new approach that would reduce the adverse effects of current treatments such as chemotherapy and radiation therapy. The researchers` results have direct implications for the treatment of acute lymphoblastic leukemia (ALL), one of the four most common types of leukemia. ALL is a cancer of the bone marrow and blood that progresses rapidly without treatment. Current treatments consist of chemotherapy and radiation therapy, which are both highly toxic and non-specific, meaning that they damage healthy cells as well as tumour tissues."Even when effective, patients can suffer dramatic side effects from these treatments," Dr. Moroy, who is also Director of the Hematopoiesis and Cancer research unit at the IRCM and corresponding author of the study said.
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