London: A novel drug dexpramipexole may help slow symptom progression in the neurodegenerative disease amyotrophic lateral sclerosis (ALS), a new study has suggested.It is believed that the drug, dexpramipexole, work by preventing dysfunction of mitochondria – the subcellular structures that provide most of a cell’s energy.“Today there are only two FDA-approved drugs used to treat ALS – riluzole, which extends life about 10 percent, and Nuedexta, which treats the emotional instability that characterizes ALS and other neurological disorders,” said Merit Cudkowicz, MD, director of the Massachusetts General Hospital (MGH) Neurology Clinical Trials Unit and ALS Center, lead author of the study.“We need more therapies to slow, halt and ultimately reverse the course of disease and also therapies to treat the symptoms,” he noted.
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