Sydney: The absence of related protein molecules, Puma and Bin, prompts immune cells to turn against human organs they are meant to protect and cause type-1 diabetes and rehumatoid arthiritis, known as autoimmune diseases.Daniel Gray and colleagues from the Walter and Eliza Hall Institute`s Molecular Genetics of Cancer division and the University of Ballarat, have discovered that these pair of protein molecules work together to kill so-called `self-reactive` immune cells that are programmed to attack the body`s own organs.Autoimmune diseases, such as type-1 diabetes, rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis, develop when immune cells launch an attack on the body`s own cells, destroying important body organs or structures, the journal "Immunity" reports.
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