Washington: Patients with type 2 diabetes have a 20 percent increased risk of developing blood cancers, such as non-Hodgkin lymphoma, leukemia and myeloma, according to a new meta-analysis.The findings add to the growing evidence base linking diabetes and certain types of cancer.“I think when most people think about diabetes-related illnesses, they think of heart disease or kidney failure, but not necessarily cancer,” said lead author Jorge Castillo, M.D., a hematologist/oncologist with The Miriam Hospital.“But when you consider that more than 19 million Americans have been diagnosed with diabetes – not to mention the millions more who are either undiagnosed or will be diagnosed in the future – a 20 percent increased risk of blood cancer is quite significant,” Castillo stated.While diabetes has been previously associated with other types of cancer, such as liver and pancreatic cancer, there have been few connections to blood cancers. Researchers are still unclear what causes the vast majority of these malignancies, which include cancers of the blood, bone marrow, and lymph nodes and affect more than 100,000 Americans each year.Castillo and colleagues analyzed 26 previously published research articles on the association between type 2 diabetes – the most common form of the disease – and the incidence of lymphoma, leukemia and myeloma. The meta-analysis included more than 17,000 cases of type 2 diabetes and blood cancer worldwide.They concluded patients with type 2 diabetes have increased odds of developing leukemia, myeloma and non-Hodgkin lymphoma, as well as a subtype of non-Hodgkin lymphoma known as peripheral T-cell lymphoma. They did not find any associations with Hodgkin lymphoma.
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