Washington: Quickly clearing out defective proteins in the brain may prevent loss of nuerons in Huntington`s disease, a genetic brain disorder that leads to uncontrolled movements and mental decline, scientists say. The speed at which damaged proteins are cleared from neurons may affect cell survival and may explain why some cells are targeted for death in neurodegenerative disorders, researchers said. In Huntington`s disease and many other neurodegenerative disorders, proteins that are misfolded (have abnormal shapes), accumulate inside and around neurons and are thought to damage and kill nearby brain cells.
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