Washington: A Case Western Reserve University researcher has discovered novel antivirulence drugs that, without killing the bacteria, render Methicillin Resistant Staphylococcus Aureus (MRSA) and Streptococcus pyogenes, commonly referred to as strep, harmless by preventing the production of toxins that cause disease.Menachem Shoham, PhD, associate professor of biochemistry at Case Western Reserve University School of Medicine,MRSA infections are a growing public health concern, causing thousands of deaths per year. It is the most prevalent bacterial pathogen in hospital settings and in the community at large.The problem has become increasingly severe as the bacteria have developed a resistance to antibiotics. As result, health care providers are running out of options to treat patients suffering from antibiotic-resistant infections, like MRSA and strep, creating a dire need for alternative treatments and approaches.“Staph bacteria are ubiquitous and normally do not cause infections, however, occasionally these bacteria become harmful due to their secretion of toxins,” said Dr. Shoham.
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