Washington: In a study on obese mice, Johns Hopkins researchers have found that that the impact of dieting and losing weight benefits the heart health of the young, but not the older ones. The researchers found that poor heart function in young obese mice can be reversed when the animals lose weight from a low-calorie diet. However, older mice, who had been obese for a longer period of time, did not regain better heart function after they were on the same low-calorie diet."Our research indicates that the longer mice are obese, the greater the risk that their heart damage is irreversible," said Majd AlGhatrif, M.D., the first author of the study and an assistant professor of medicine at the Johns Hopkins University School of Medicine."We don`t know whether the same principle would apply to humans as well, and if so, what the turning point would be. But the basic message is that losing weight sooner rather than later would be more beneficial," said Lili Barouch, M.D., the senior author of the study and a cardiologist and assistant professor of medicine at the Johns Hopkins University School of Medicine.
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