11 new genetic variations linked to Type 2 Diabetes
Washington: Scientists from Michigan Technological University have identified 11 new genetic variants linked to Type 2 diabetes.
With the help of Ensemble Learning Approach (ELA) software, the researchers have isolated 11 variations within genes—called single nucleotide polymorphisms, SNPs or snips, associated with Type 2 diabetes.
"With chronic, complex diseases like Parkinson``s, diabetes and ALS [Lou Gehrig``s disease], multiple genes are involved," said Qiuying Sha, an assistant professor of mathematical sciences.
“You need a powerful test," Sha added.
To test their model, the researchers analyzed over 1,000 people in the United Kingdom, half with Type 2 diabetes and half without.
They identified 11 SNPs that, singly or in pairs, are linked to the disease with a high degree of probability.
ELA is used to compare the genetic makeup of unrelated individuals to sort out disease-related genes.
The team has also developed another approach, which uses a two-stage association test that incorporates founders`` phenotypes, called TTFP, that can examine the genomes of family members going back generations.
The team has published their findings in the European Journal of Human Genetics.
More from India
More from World
More from Sports
More from Entertaiment
- Ceasefire violations by Pak: Should India carry out surgical strike part-II?
- Pak High Commission staffer grilled for spying, asked to leave India
- Panel discussion on the need of Pakistan's ambassador in India
- Meet Lynlee Hope - Texas baby who was 'born' twice!
- Intelligence agencies warn of firing by Pakistan along LoC, international border
- Pakistan's brutality exposed; `Black Day` protesters thrashed in PoK - Video goes viral
- Pakistan High Commission staffer, briefly detained for espionage, asked to leave India in 48 hours
- Diwali 2016: Dhanteras Puja timings, Tithi and Vidhi
- Pakistan declares Indian High Commission official persona non grata, asks him to leave country
- UPA govt thought of attacking Lashkar HQ, training camps after 26/11 strike, claims ex-NSA Shivshankar Menon