Mumbai: Upto 80 per cent of criticallyill newborns in India suffer from Acute Kidney Injury (AKI),also known as Acute Renal Failure, experts from Batra Hospitaland Medical Research Centre said Wednesday. "As many as 30?50 per cent of patients in theIntensive Care Unit and about five per cent of hospitalisedchildren overall have this condition. Again, Chronic KidneyDisease (CKD) together with End Stage Renal Disease (ESRD) hasa worldwide incidence of 75?350 per million population," DrSanjeev Bagai, CEO and Consultant Pediatrician andNephrologist, Batra Hospital said on the eve of World KindeyDay.
Asked whether there would be some early diagnostictool available, Bagai said, "In the near future there would benovel biomarkers for early detection and management of kidneyinjury including Urine panel of NGAL, IL-18, KIM-1, and Plasmapanel of NGAL and Cystatin C. These biomarkers are sensitivemuch before rise in Serum creatinine." The symptoms and signs are often subtle and hidden. Laboratory investigations include detailed blood and urineanalysis with radio imaging are must. "Detailed history taking and clinical examination isthe key to early diagnosis. The mortality in AKI remains high(10-19 per cent) with a five-year survival of severe AKI at 80per cent," said Dr Ramesh Kumar, Senior ConsultantNephrologist, Batra Hospital, located in Delhi. PTI
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