Washington: In a bid to tackle the growing problem of alcoholism, a new vaccine that gives alcoholics an immediate and heavy hangover will soon be tested in India after preclinical trials in Chile, researchers say.The preclinical trial preludes the phase one clinical trial in India, when doctors will inject people with the vaccine for the first time. If all goes well, the vaccination could be available as soon as two years from now, Dr Juan Asenjo, director of the Institute for Cell Dynamics and Biotechnology at Universidad de Chile, was quoted as saying.The vaccine, which would be effective for between six months and a year, works by sending a biochemical message to the liver telling it not to express genes that metabolise alcohol.Normally, the liver turns alcohol into the hangover-causing compound called acetaldehyde which is then broken down by a metabolising enzyme.If someone who`s been vaccinated tries to drink alcohol, they will immediately experience severe nausea, accelerated heartbeat, and general discomfort. Once the vaccine has been administered it cannot be reversed, the report said.Asenjo thinks that although the vaccine is not a cure-all, it could provide an important first step.
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