London: Common painkillers such as ibuprofen and diclofenac as well as branded pain drugs from Pfizer Inc, Merck & Co Inc and Novartis AG can increase the risk of heart attacks and strokes, a review found on Wednesday.Scientists from Bern University in Switzerland analyzed data from 31 trials involving more than 116,000 patients taking either naproxen, ibuprofen, diclofenac, Pfizer`s Celebrex, or celecoxib, Merck`s Arcoxia, or etoricoxib, Merck`s Vioxx, or rofecoxib, Novartis` Prexige, or lumiracoxib, or a placebo, to try to give an estimate of the heart risks of such medicines.
Merck`s Arcoxia and the generic drug diclofenac were linked with around four times the risk of cardiovascular death."Although uncertainty remains, little evidence exists to suggest that any of the investigated drugs are safe in cardiovascular terms," said Peter Juni of Bern University`s Institute of Social and Preventive Medicine, who led the study.Bureau Report
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