Washington: Patients treated with a short course of antidepressants after a stroke have significantly greater improvement in physical recovery than patients treated with a placebo, a University of Iowa study has found.
In addition, the effect compared to placebo was observed even after controlling for patients` age, total hours of rehabilitation therapy and initial severity of stroke.In the study, 83 patients who had recently had a stroke were randomly assigned to receive antidepressants (54 patients) or placebo (29 patients) for three months. The patients` physical, cognitive and psychiatric symptoms were assessed every three months for one year. Thirty-six of the patients who received antidepressants and 25 of the patients on placebo completed the one-year study.Using a global measure of overall physical and motor disability, the researchers showed that antidepressants significantly reduced physical disability over the one-year period compared to placebo.The study is detailed in the American Journal of Geriatric Psychiatry Feb. 24.ANI
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