Washington: An immunologist has said that with some prompting, the protein STING can turn down the immune response or even block its attack on healthy body constituents like collagen, insulin and the protective covering of neurons - targets of the debilitating diseases.Medical College of Georgia researchers saw STING’s critical role play out after they injected into the bloodstream submicroscopic DNA nanoparticles, engineered carriers for delivering drugs or genes into cells.They learned that the magic is in STING, which recognizes the molecule that senses the DNA then prompts release of IDO, or indoleomine 2,3-dioxyegenase.Dr. Andrew L. Mellor, immunologist at the Medical College of Georgia at Georgia Regents University said that the fact that STING is actually part of the DNA-sensing pathway tells us something we did not know before.
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