Bacteria dodging antibiotics? Not any more
London: Not many know that there are few stubborn bacteria that become dormant when exposed to antibiotics, only to awaken later to begin their dreadful task.
In a breakthrough research, the mechanism by which some bacteria are able to survive antibacterial treatment has been revealed at Hebrew University in Jerusalem - paving the way to control such 'persistent' bacteria in near future.
The researchers found that when antibiotics attack these bacteria, the HipA toxin - naturally occurring toxin triggering dormancy of the bacteria - disrupts the chemical "messaging" process necessary for nutrients to build proteins.
Bacteria treat this condition as 'hunger signal', go into an inactive state in which they are able to survive until the antibacterial treatment is over and they can resume their harmful activity, said the research published in the journal Nature Communications.
“When you treat using antibiotics, there will always be some bacteria that survive. If we manage in the future to introduce a substance that deals with the biological mechanism that the study uncovered, antibiotics will be more effective,” said Gadi Glaser of faculty of medicine. He was assisted by Nathalie Balaban of Racah Institute of Physics.
Until now, it had been known that there is a connection between these kind of bacteria and the naturally occurring toxin HipA in the bacteria, but scientists did not know the cellular target of this toxin and how its activity triggers dormancy of the bacteria, added the research.
The research on persistent bacteria, being conducted in Balaban's lab for several years, would be combined with the work being done in Glaser's lab focusing on combating persistent bacteria - leading to more effective treatment for bacterial infections.
More from India
More from World
More from Sports
More from Entertaiment
- One year of Modi govt: PM promises to fulfil aspirations
- Watch: Mumbai cops find new secret agents in housewives!
- Hundreds die as heat wave continues in India
- 2G scam: Ex-TRAI chief alleges Manmohan Singh had warned him to cooperate
- Pranab Mukherjee defends Bofors scam, says it was just a media trial
- Salman Khan attends sister Arpita's wedding reception in Mandi
- Zee Media's mega survey on Modi govt
- Zee Media Exclusive: Vidya Balan chats about 'Hamari Adhuri Kahani'
- Para athlete Deepa Malik complains of callous service by Air India
- Smriti Irani visits Amethi, promises to pay insurance money to 25,000 women
- One year of Modi govt: Amit Shah addresses media
- I eat beef, can somebody stop me?: Kiren Rijiju hits back at Naqvi
- Delhi: Visually impaired boy scores 91.4% in CBSE 12th Board exams
- MP: 14-year-old boy works as bonded labour since 2009
- BBV: What challenges lie ahead of Modi govt?
- One year of NDA govt: PM Modi writes open letter to nation, promises to transform India
- Arpita-Aayush wedding reception: Salman Khan spreads love in Mandi, says `hum aapke hain`
- World optimistic about India: PM Narendra Modi on 1 year of NDA govt
- MSBSHSE Class 12th HSC results 2015 to be declared at 1pm tomorrow
- Bharatiya Janata Party lacks majority for Ram Temple, Article 370: Amit Shah
- Rahul Gandhi takes a dig at one year of Modi govt, wishes 'happy birthday' to 'suit-boot ki sarkar'
- CBSE Class 10 Board Result 2015 (cbse.nic.in, cbseresults.nic.in) postponed?
- AAP govt moves resolution against MHA notification: As it happened
- Check mahresult.nic.in for MSBSHSE Maharashtra Class 12 HSC Result 2015
- CBSE Class 10 Board Result 2015 to be announced on May 28
- Maharashtra MSBSHSE HSC Result 2015 on mahresult.nic.in
- Heatwave kills 90 more in Andhra, Telangana; toll crosses 800
- Gujjars adamant on holding talks in Bayana; rail tracks remain blocked
- CBSE 10th result to be declared tomorrow
- I was misquoted, says Kiren Rijiju on 'beef' remark