Bacteria that may lead to inflammatory bowel disease identified
Washington: A study, led by Harvard School of Public Health researchers, has found that certain bacteria that inhabit the intestine provide the environmental trigger that initiates and perpetuates chronic intestinal inflammation in individuals who are genetically susceptible to inflammatory bowel disease (IBD).
Inflammatory bowel disease results from a loss of homeostasis, or balance, between the immune system and the microbes that inhabit the intestine.
"In this study, we identified two microbes that instigate gut inflammation that leads to inflammatory bowel disease in mice," said lead investigator Wendy Garrett, assistant professor of immunology and infectious diseases at HSPH.
"We show using both metagenomic and conventional culture techniques that an individual’s genetic background influences what bacteria reside within his or her intestine. Several studies are currently underway examining the intestinal microbial communities of patients with IBD and we are looking forward to exploring the role of the Enterobacteriaceae we have identified in patients with IBD."
The study appears in the September 16, 2010, edition of Cell Host & Microbe.
More from India
More from World
More from Sports
More from Entertaiment
- Armoured cars now mandatory to accompany security forces in Kashmir
- Panel discussion on breaking the law over cow security
- Panel discussion on breaking the law over cow security - Part II
- Panel discussion on breaking the law over cow security - Part III
- When will Indian roads become free from potholes and open manholes?
- Rio Olympics 2016: World No.1 golfer Jason Day withdraws over Zika virus fears
- Banks asset quality stress needs to be dealt first: RBI Governor
- Congress accuses TMC government of taking soft stand on BJP
- J&K convoy ambushes: 15 troops killed in last one year
- J&K govt orders probe into Humhama land grabbing issue