Being overweight in early adulthood may double risk of kidney disease in older age
Washington: Those who are overweight starting in early adulthood (ages 26 or 36 years) may be twice as likely to have chronic kidney disease at age 60 to 64 years than those who are not overweight, according to a new study.
Larger waist-to-hip ratios ("apple-shaped" bodies) during middle age are also linked with chronic kidney disease at age 60 to 64 years.
The findings emphasize the importance of excess weight as a risk factor for chronic kidney disease (CKD).
Because many populations across the globe continue to gain excess weight, Richard Silverwood, PhD, Dorothea Nitsch, MD (London School of Hygiene and Tropical Medicine, in England), and their colleagues conducted a study to see what sort of effect being overweight or obese might have on kidney health.
The researchers analyzed information from the Medical Research Council National Survey of Health and Development, a sample of children born in one week in March 1946 in England, Scotland, and Wales. A total of 4,584 participants had available data, including body mass index at ages 20, 26, 36, 43, 53, and 60 to 64 years.
They found that participants who were overweight beginning early in adulthood (ages 26 or 36 years) were twice as likely to have CKD at age 60 to 64 years compared with those who first became overweight at age 60 to 64 years or never became overweight.
The link between overweight and CKD was only in part explained by taking diabetes and hypertension into account.
Larger waist-to-hip ratios ("apple-shaped" bodies) at ages 43 and 53 years were also linked with CKD at age 60 to 64 years.
"We estimated that 36 percent of CKD cases at age 60 to 64 in the current US population could be avoided if nobody became overweight until at least that age, assuming the same associations as in the analysis sample," said Dr. Nitsch.
"To our knowledge we are the first to report how age of exposure to overweight across adulthood may affect kidney disease risk," she added.
It is unclear whether the timing of overweight onset or the duration of being overweight drives the link with CKD seen in the study. Either explanation suggests that preventing excess weight gain in early adulthood could have a considerable effect on the prevalence of CKD.
Doing so appears to have a larger effect than any treatment for CKD known to date, the researchers said.
The study will appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
More from India
More from World
More from Sports
More from Entertaiment
- IAF Mirage fighter plane lands on Yamuna Expressway!
- 'Maggi' under regulatory scanner for excess amount of lead, MSG
- Watch: Michelle Obama's 'Gimme Five' fitness video
- When Subramanian Swamy shocked people at a wedding!
- Mumbaikars join hands to save Pakistani teen with rare illness
- Mumbai: Diamond export company denies job to Muslim youth
- PM Modi speaks at Golden Jubilee celebrations of poet Dinkar’s works
- Aapke Sitare: Astro prediction for May 21, 2015
- Mirage 2000 fighter jet landing was part of capability demonstration: IAF
- DNA: IAF Mirage 2000 fighter plane lands successfully on Yamuna expressway
- Vadodara: Policemen seen dancing with bar girls
- Coal scam: Naveen Jindal, Madhu Koda and others get bail
- One year of Modi govt: Arun Jaitley addresses press conference
- DNA: Osama documents show 'Indian brother in Madinah' financed al Qaeda
- ISIS executes Syrian fighter using anti-tank rocket launcher
- CBSE Class 10 Results 2015 to be announced today?
- Check Jharkhand Board jac.nic.in: Class 12th Art Results 2015 declared
- Fawad Khan doesn’t want intimate scenes with Sonam Kapoor?
- Log on to apeamcet.org AP EAMCET Results 2015: Andhra Pradesh EAMCET Marks and AP EAMCET Ranks 2015 declared
- We hire only non-Muslim candidates, diamond export firm tells Muslim youth
- Is MSG in 'Maggi' noodles harmful for you?
- Mumbai firm booked for denying Muslim MBA graduate job on religious grounds, probe ordered
- Jayalalithaa makes public appearance, meets Governor: As it happened
- New IPL rules could see Chennai Super Kings lose MS Dhoni
- `Piku` hits jackpot, does Rs 100 crore business worldwide
- Anurag Kashyap to bid goodbye to India, settle in 'cinema-friendly' France!
- IPL 2015, Qualifier 2, Chennai Super Kings vs Royal Challengers Bangalore: Preview
- Geelani's passport application incomplete, cannot be processed: MEA
- SSLC (tnresults.nic.in) TNBSE Tenth 10th Results 2015: Tamil Nadu Board Class 10th X Higher Secondary exam results 2015 declared
- CBSE Class X Results 2015 to be announced today?