New Delhi: Biotechnology major Biocon today said its drug molecule `Itolizumab`, which could be used to treat Psoriasis, has shown positive results in the Phase III trials. "Itolizumab, the first humanised anti CD-6 monoclonal antibody, successfully met the pre-specified primary endpoint of significant improvement in PASI-75 (Psoriasis Area and Severity Index) score after 12 weeks of treatment in patients with moderate to severe psoriasis compared to placebo," Biocon said in a statement. The 52-week study conducted across the country enrolled 200 patients had a 12-week placebo controlled phase, 16-week consolidation and 24-week randomised withdrawal phase, it added. Commenting on the outcome of the study Biocon CMD Kiran Mazumdar-Shaw said: "Itolizumab represents a significant advancement in the treatment of psoriasis and potentially ther autoimmune diseases with an excellent risk-benefit profile." This could possibly become the first novel biologic developed and approved from India and is an important milestone for Biocon in its pursuit of affordable innovation, she added.
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