Bitter cumin ‘a rich source of phenolic antioxidants’
Washington: Indian researchers have found that cumin, the bitter spice used as a key ingredient in curries, contains high levels of antioxidants.
Cumin, which is extensively used in traditional medicine to treat a range of diseases from vitiligo to hyperglycemia, is also considered to be antiparasitic and antimicrobial and science has backed up claims of its use to reduce fever or as a painkiller.
Reactive oxygen species (ROS), also known as free radicals, are produced as part of the metabolic processes necessary for life. Oxidative stress, however, is caused by overproduction or under-removal of these free radicals.
Oxidative stress is itself involved in a number of disorders, including atherosclerosis, neural degenerative disease, inflammation, cancer and ageing. Antioxidants are thought to mop up these free radicals, reduce oxidative stress, and prevent disease.
Phenolic compounds from plants, especially polyphenolic compounds, are often considered to be antioxidants.
Researchers from Mysore have used biochemical and biological techniques to show that seeds from bitter cumin (Centratherum anthelminticum (L.) Kuntze), a member of the daisy family, are a rich source of phenolic antioxidants.
"Bitter cumin extracts were strong antioxidants in the free radical scavenging systems tested. The extracts were also strong electron donors and hence reducing agents, another marker of antioxidation,” said the researchers from the Central Food Technological Research Institute.
“In biological tests bitter cumin inhibited the oxidation of liposomes (used as a model for cell membrane oxidation) and offered complete protection against DNA damage," they said.
The study was published in BioMedCentral`s open access journal BMC Complementary and Alternative Medicine.