Washington: Why does one person become anorexic and another obese? A study shows that reward circuits in the brain are sensitized in anorexic women and desensitized in obese women.Guido Frank, director of the Developmental Brain Research Program, University of Colorado School of Medicine and colleagues used functional magnetic resonance imaging (fMRI) to examine brain activity in 63 women who were either anorexic or obese. They were compared to women considered "normal" weight.Participants were visually conditioned to link certain shapes with either a sweet or a non-sweet solution and then received the taste solutions expectedly or unexpectedly. This task has been tied with brain dopamine function in the past, the journal Neuropsychopharmacology reports.
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