Chicago: Three in 10 women take the common breast cancer drug Femara to treat infertility, even though it could increase risks to the baby, US researchers said on Friday.They said the drug is often prescribed "off-label" to treat infertility, even though it is classified by the US Food and Drug Administration as posing a pregnancy risk.And a study of health claims suggests policies by health insurers to only pay for the drug`s approved uses could improve both the care and safety of the women who take it.
Doctors that treat infertility say they use the drug in women with ovulation problems.According to a website for the Advanced Fertility Center of Chicago, when the enzyme aromatase is blocked by the drug it causes estrogen levels in young women to fall, triggering the release of follicle stimulating hormone or FSH, which causes women to ovulate.And they said the Canadian study was too small, and its trial design has been seen as flawed.Bureau Report
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