Calcium supplementation does not increase coronary heart disease in elderly women
Washington: A study has found that calcium supplementation, with or without vitamin D, does not increase coronary heart disease or cause mortality risk in elderly women.
The study was presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
The investigators, from centres in Australia, Denmark and the USA, undertook a meta-analysis of randomized controlled trials of calcium supplements with or without vitamin D.
They searched for two primary outcomes: coronary heart disease and all-cause mortality verified by clinical review, hospital record or death certificate.
The Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE databases were searched from January 1, 1966 - May 24, 2013 for potentially eligible studies, reference lists were checked, and trial investigators were contacted where additional data was required. Trial data were combined using a random-effects meta-analysis to calculate relative risk of heart disease events in participants supplemented with calcium.
The meta-analysis showed that calcium supplementation with or without vitamin D does not increase coronary heart disease or all-cause mortality risk in elderly women.