Washington: Swedish researchers have shown that a derivative of cholesterol is necessary for the formation of brain cells by conducting experiments on mice.
They are also the type of cell that dies in Parkinson``s disease, Prof. Arenas adds.The current study has also shown that embryonic stem cells, cultivated in the laboratory, form more dopamine-producing nerve cells if they are treated with oxidised cholesterol. According to the study report, the same treatment also reduced the tendency of the stem cells to show uncontrolled growth."Oxysterol contributes to a safer and better cultivation of dopamine-producing cells, which is a great advancement since it increases the possibility of developing new treatments for Parkinson s disease," says Prof. Arenas.
The researchers hoped that it will one day be possible to replace dead cells in the brains of Parkinson``s patients with transplanted cultivated dopamine-producing cells. Such cells can also be used to test new Parkinson``s drugs, they believe. ANI
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