Washington: Deep brain stimulation (DBS) - in the form of high-frequency stimulation (HFS) of the nucleus accumbens shell (AcbSh) - in alcoholic rats consistently reduced alcohol consumption in the animals, a new study has found.
The finding suggests that the AcbSh could be a target in the future for surgical intervention of addiction.
In the study, researchers used alcohol-preferring (P) rats as an animal model for alcoholism, with the study assessing whether HFS of the AcbSh in P rats would affect their alcohol consumption.
For the study, rats underwent 10 weeks of daily one-hour access to EtOH to establish alcoholism.
The finding was revealed during the 81st American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.