Washington: Grapefruit could hold the key to tackling diabetes, a new study has found.Naringenin, an antioxidant derived from the bitter flavor of grapefruits and other citrus fruits, may cause the liver to break down fat while increasing insulin sensitivity, a process that naturally occurs during long periods of fasting.
In fact, the compound seems to mimic the actions of other drugs, such as the lipid-lowering Fenofibrate and the anti-diabetic Rosiglitazone, offering the advantages of both. If the results of this study extend to human patients, this dietary supplement could become a staple in the treatment of hyperlipidemia, type-2 diabetes, and perhaps metabolic syndrome. "It is a fascinating find. We show the mechanism by which naringenin increases two important pharmaceutical targets, PPARa and PPAR, while blocking a third, LXRa. The results are similar to those induced by long periods of fasting,” said Yaakov Nahmias, of the Hebrew University of Jerusalem the paper`s senior author. ANI
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