Washington: Exposing pregnant mice to low doses of the chemical tributyltin (TBT), which was used in marine antifouling paints and is used as an antifungal agent in some paints, certain plastics and a variety of consumer products, can lead to obesity for multiple generations without subsequent exposure, researchers say.After exposing pregnant mice to TBT at low concentrations, similar to those found in the environment and in humans, researchers from UC Irvine observed increased body fat, liver fat and fat-specific gene expression in liver and stem cells in mouse "children," "grandchildren" and "great-grandchildren."
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