New York: Researchers, led by an Indian-origin scientist, have identified genes which help female mice and some other mammals delay the onset of pregnancy. Unlike in humans, the remarkable ability, known as embryonic diapause, is a temporary state of suspended animation that occurs when environmental conditions are not favourable to the survival of the mother and the newborn. A new study, published in the journal Open Biology, reveals the molecular mechanism responsible for pausing and resuming a pregnancy. After an egg is fertilised, it forms a cluster of cells known as a blastocyst, which implants in the wall of the mother`s uterus, `LiveScience` reported. However, in diapause, the blastocyst is prevented from implanting and preserved in an dormant state until pregnancy resumes. How this process occurred was a mystery till now.Researcher Sudhansu Dey, from Cincinnati Children`s Research Foundation, and colleagues were studying the process of embryo implantation in mice when they noticed that a gene called MSX1 was very active just before implantation.
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