Washington: A research team led by Brown University has come up with promising results for earlier diagnosis of Hepatocellular carcinoma, which is the most common cancer to strike the liver. In lab tests, the team used gold nanoparticles ringed by a charged polymer coating and an X-ray scatter imaging technique to spot tumour-like masses as small as 5 millimeters. It is the first time that metal nanoparticles have been used as agents to enhance X-ray scattering signals to image tumour-like masses.
In lab tests, the nontoxic gold nanoparticles made up just 0.0006 percent of the cell``s volume, yet the nanoparticles had enough critical mass to be detected by the X-ray scatter imaging device. "We have shown that even with these small numbers, we can distinguish these [tumor] cells," said Rose-Petruck. The study has been detailed in the American Chemical Society journal Nano Letters. ANI
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