Washington: A study has indicated that women whose breasts appear dense on mammograms are at a higher risk of breast cancer and their tumours are more likely to have certain aggressive characteristics than women with less dense breasts.Mammographic breast density--a reflection of the proportions of fat, connective tissue, and epithelial tissue in the breast--is a well-established risk factor for breast cancer. Women with higher amounts of epithelial and stromal tissue have higher density and higher risk. However, it has not been clear whether breast density was associated with specific tumour characteristics and tumour type.
The authors concluded that higher mammographic density is associated with more aggressive tumour characteristics and also with DCIS. “Our results suggest that breast density influences the risk of breast cancer subtypes by potentially different mechanisms,” they wrote.“Further studies are warranted to explain underlying biological processes and elucidate the possible pathways from high breast density to the specific subtypes of breast carcinoma,” they added. The study has been published online in the Journal of the National Cancer Institute. ANI
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