Washington: Scientists have found that different types of happiness have different effects on the human genome.Researchers from UCLA`s Cousins Center for Psychoneuroimmunology and the University of North Carolina found that people who have high levels of eudaimonic well-being - kind of happiness that comes from having a deep sense of purpose and meaning in life - showed very favourable gene-expression profiles in their immune cells.They had low levels of inflammatory gene expression and strong expression of antiviral and antibody genes.However, people with relatively high levels of hedonic well-being - the type of happiness that comes from consummatory self-gratification (think most celebrities) - actually showed just the opposite.They had an adverse expression profile involving high inflammation and low antiviral and antibody gene expression.For the last decade, Steven Cole, a UCLA professor of medicine and a member of the UCLA Cousins Center, and his colleagues, including first author Barbara L. Fredrickson at the University of North Carolina, have been examining how the human genome responds to stress, misery, fear and all kinds of negative psychology.In the present study, the researchers drew blood samples from 80 healthy adults who were assessed for hedonic and eudaimonic well-being, as well as potentially confounding negative psychological and behavioral factors.The team used the CTRA gene-expression profile to map the potentially distinct biological effects of hedonic and eudaimonic well-being.
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