A new study has found that heavy beer drinkers who have a specific genetic variant in the cluster of three genes that metabolize alcohol are at significantly higher risk of developing non-cardia gastric cancer. Study results also showed that the same risk is also elevated (but not as significantly) for heavy beer drinkers who do not have the variant, known as rs1230025, and for non-drinkers who have rs1230025 or rs283411. "This is a classic gene-environment interaction," said Eric Duell, senior epidemiologist in the Cancer Epidemiology Research Program at the Catalan Institute of Oncology in Barcelona, Spain. "Having both of these risks - heavy beer consumption and rs1230025 - appears to be worse in terms of gastric cancer risk than having just one or neither."
The research was presented at the AACR 102nd Annual Meeting 2011, April 2-6.ANI
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