High fiber diet halts prostate cancer growth
Washington: Eating a high-fiber diet may help patients with prostate cancer stop the disease from progressing, according to a new study led by Indian-origin researchers.
The study compared mice fed with of inositol hexaphosphate (IP6), a major component of high-fiber diets, to control mice that were not. Then the study used MRI to monitor the progression of prostate cancer in these models.
"The study`s results were really rather profound. We saw dramatically reduced tumor volumes, primarily due to the anti-angiogenic effects of IP6," says Komal Raina, PhD, research instructor at the Skaggs School of Pharmacy and Pharmaceutical Sciences, working in the lab of CU Cancer Center investigator and School of Pharmacy faculty member, Rajesh Agarwal, PhD.
Basically, feeding with the active ingredient of a high-fiber diet kept prostate tumors from making the new blood vessels they needed to supply themselves with energy. Without this energy, prostate cancer couldn`t grow. Likewise, treatment with IP6 slowed the rate at which prostate cancers metabolized glucose.
Possible mechanisms for the effect of IP6 against metabolism include a reduction in a protein called GLUT-4, which is instrumental in transporting glucose.
"Researchers have long been looking for genetic variations between Asian and Western peoples that could explain the difference in prostate cancer progression rates, but now it seems as if the difference may not be genetic but dietary. Asian cultures get IP6 whereas Western cultures generally do not," Raina says.
The research provides the cover image of this month`s issue of the journal.
The study has been published in journal Cancer Prevention Research.
More from India
More from World
More from Sports
More from Entertaiment
- Dr Subhash Chandra Show: Aspiring for more than what you have!
- Mathura SSP receives death threat letter, message for PM Modi
- Reservation issue: Police register case against Bainsla, 20 others
- Zee Media exclusive interview with Haryana CM Manohar Lal Khattar
- Zee Media exclusive chat with 'Welcome to Karachi' cast
- Watch: Fast N Facts @ 7:30pm
- Girl in Punjab's Pathankot quit studies for fear of eve-teasing
- Special: Furious over rising water crisis, people take to the streets
- UP Minister allegedly threatens, abuses Gonda businessman
- Manali: Heavy corruption found in environmental taxes
- Couple in Bihar asked to pay Rs 50,000 as 'tax' for inter-caste marriage
- Aapke Sitare: Astro prediction for May 24, 2015
- Watch: Fast N Facts @ 7:30pm
- One year of Modi govt: How satisfied is the common man?
- One year of Modi govt: How satisfied is the common man? Part-2
- IPL 2015 Final: MI vs CSK - As it happened...
- Heatwave continues in North India; death toll in Andhra Pradesh, Telangana more than 400
- CBSE.nic.in 12th XII Results 2015: CBSE Board (cbseresults.nic.in) Class 12th XII Exam Results 2015 to be announced on May 25
- Heatwave kills 223 in AP, Telangana, Chandrababu Naidu announces compensation; Delhi records hottest day
- CBSE 12th Result 2015 to be announced on Monday
- IPL 2015 final: Mumbai Indians thrash Chennai Super Kings by 41 runs to lift second title
- Death threat to PM Narendra Modi ahead of Mathura rally sends police into tizzy
- Organisation demands re-examination of AIPMT 2015
- Kejriwal completes 100 days in office, AAP says centre 'shadow boxing' over row with LG
- CBSE Class 12th Board Results 2015 to be announced on Monday, May 25
- Online filing of applications for UPSC civil services exam begins
- No alliance with JD-U in Bihar: BJP
- Not just today, Muslims feeling alienated since 1947: Najma Heptulla
- Preity Zinta missed crew of 'ABCD 2' on 'Nach Baliye 7'
- Congress comes out with scathing 'report card' on PM Narendra Modi's 1yr rule